Wisut pulled away from a packed leaderboard by firing a closing 3-under-par 68 to beat compatriot Sattaya Supupramai and Vietnam's Michael Tran by two shots.
Sattaya shot 68 and Tran 70 in the final event of the 2013-14 Asean PGA Tour season.
Wisut complained he had been struggling with his game for the past six months battling a swing change and putting problems. The last time he won an event was the 2011 Sabah Masters, the year he also claimed the Asean PGA Order of Merit title.
"I am so happy. It all came right this week and I feel confident going in the new year," said Wisut, who finished the event 8 under par.
He also faced the added pressure this week of fighting for playing rights this year. He had no status on a Tour but his winning cheque, worth US$12,187, moved him from 13th to third place on the final Order of Merit to secure one of the four OneAsia cards available.
"I don’t know what I would have done if I not got my OneAsia card," he said. "It's very important. I'm more happy than when first time I won this title two years ago."
Wisut, Tran and Thailand's Ratchapol Jantavara started the day tied for the lead and it was a tight battle all day with the lead changing hands many times.
Ratchapol ended tied for fourth, four shots behind the winner, along with defending champion Antonio Lascuna of the Philippines, Singaporean Mardan Mamat, and Filipino veteran Frankie Minoza.
Thailand's Kwanchai Tannin wrapped up the Order of Merit title by finishing in 13th place at one over. He topped the Merit list, and secured a OneAsia card, with earnings of US$35,630 – an Asean PGA Tour record.
Namchok Tantipokhakul of Thailand finished second on the list with $23,693 and earned the second OneAsia card. Wisut won the third card and Ratchapol the fourth.