Mr Obama's trip to Japan, during which he will meet with Japanese Prime Minister Shinzo Abe, was arranged as Japan is seeking to demonstrate close bilateral ties in order to better deal with regional issues such as North Korea and a rising China.
Mr Obama and Mr Abe will discuss how to deepen their security and economic ties including through the Trans-Pacific Partnership free trade agreement and "expand our cooperation on a range of diplomatic challenges in Asia and globally," the White House said.
Details about Mr Obama's visit to Japan such as the date and whether he will be accommodated as a state guest as proposed by Japanese Foreign Minister Fumio Kishida have not been decided, a White House official said.
Tokyo and Washington are working on realising Mr Obama's visit, which will be the first such in three and half years, on April 22 and 23, a Japanese government official said.
In South Korea, Mr Obama will meet with Korean President Park Geun Hye and discuss recent developments in North Korea and efforts to promote denuclearization as well as the bilateral free trade pact, the White House said.
Mr Obama will also visit Malaysia to meet with Malaysian Prime Minister Najib Razak and then go to the Philippines to meet with Phipippine President Benigno Aquino, it said.
The US president pledged in 2011 to focus on the Asia-Pacific region describing US mission there as "a top priority."
Mr Obama has visited Japan twice since he became US president in 2009.
It will be the first visit to Japan by Mr Obama since the devastating earthquake and tsunami struck the northeastern region in March 2011 and caused the worst nuclear crisis since Chernobyl at the Fukushima Daiichi power plant.
Mr Obama cancelled a trip to the Philippines, Malaysia, Indonesia and Brunei planned for October as he had to deal with the partial government shutdown over budget issues.