The move marks a further international network expansion of the airline which until recently focused on the domestic market in direct competition with arch rival VietJet Air.
Jetstar Pacific's announcement of the service came shortly after the privately owned VietJet Air said it would boost the frequencies on the Bangkok-Ho Chi Minh City route to twice a day starting on Sept 12. This will double VietJet Air's capacity to over 5,000 seats a week and is said to be in response to stronger demand.
Jetstar Pacific, which operates as part of the low-cost carrier Jetstar Group linked with Australia's Qantas, will use the single-aisle Airbus 320, similar to that deployed by VietJet Air, for the new service.
The flight will depart from Ho Chi Minh City at 1.05pm and arrive in Bangkok at 2.35pm. The return flight will leave at 3.20pm from Bangkok, arriving in Ho Chi Minh City at 4.50pm.
The Ho Chi Minh City-based airline currently serves Hanoi, Danang, Vinh, Haiphong, Buon Ma Thuot, Nha Trang, Phu Quoc and Hue.
Bangkok will be Jetstar Pacific's second international destination after Macau.