The most popular animal in Thailand was put on board a Thai Airways International "Flight of Love" charter from Chiang Mai airport to Chengdu in Sichuan province.
Lin Ping is scheduled to return to Thailand in about a year.
About 30 hard-core fans won a draw to join the panda on the two-and-a-half hour flight. They also received two nights' accommodation as part of the tour packages worth from 26,500 to 50,000 baht.
The Du Jiangyan Giant Panda Base of the China Conservation and Research Centre has prepared six male pandas for the four-year-old Lin Ping to pick as her partner once she arrives in Chengdu, former prime minister Somchai Wongsawat told reporters.
Mr Somchai, in a farewell ceremony, thanked China for giving the kingdom a chance for Lin Ping to be born here. Lin Ping was born on May 27, 2009 to Chuang Chuang and Lhinhui, who were brought to Thailand 10 years ago.
Ning Fukai, the Chinese ambassador to Thailand, returned the favour, saying that China also thanked Thailand for taking a good care of the panda.
The Lin Ping trip signified cooperation between the two countries in breeding and conserving pandas, he added.
Lin Ping would spend another two hours for customs clearance before being taken on a one-hour drive to her new home at the Chinese centre.
Chiang Mai Zoo staged farewell events or the whole week and prepared the panda for her first flight including putting her in a cage at the zoo to make her familiar with her new surroundings, conducting blood tests and monitoring her emotions for more than a week.
She was accompanied by veterinarian Kannika Jantarangsri, head of the conservation section of the zoo. She was making sure that Lin Ping would not go hungry on the Thai flight, with plenty of bamboo and other food on hand.
Car tyres and plastic footballs were also put in the cage to help the panda relax and enjoy the flight.
A superstar at Chiang Mai Zoo, Lin Ping has been visited by 370,000 people since last September, generating revenues of 15.8 million baht, according to the zoo.
Lin Ping left the airport at 10.30am after a 90-minute ceremony chaired by Kanchana Silpa-archa, the adviser to the Tourism Authority of Thailand board.
The sendoff event began at 9am with the Chinese and Lanna traditional dances, and a parade to take Lin Ping from the zoo to the airport with panda mascots in traditional outfits.